Fungal surface-active proteins unveil secrets of the tubular lifestyle, fitness, and speciation
          發布時間 :2020-12-17  閱讀次數 :9281

          微生物代謝國家重點實驗室學術交流例會暨國重實驗室科技創新課程

          報告題目:Fungal surface-active proteins unveil secrets of the tubular lifestyle, fitness, and speciation

          報告人: Professor Irina S. Druzhinina (Nanjing Agricultural University)

          時間: 2020年12月25日(星期五)10:00-11:00

          地點: 閔行校區生命藥學樓樹華多功能廳

           

          簡介/Brief Bio:

          Irina S. Druzhinina is Professor at the Nanjing Agricultural University, she is a chair of the International Sub-commission on Trichoderma and Hypocrea of IUMS International Commission on Taxonomy of Fungi (ICTF), member of steering committee of fungal barcode initiative and reviewer for national research funds in Australia, Belgium, Germany (DFG), Netherlands, Russia, Israel, and Kazakhstan. Prof. Druzhenina's articles have more than 8400 citations with over 140 publications in peer-reviewed journals. Prof. Druzhinina also serves as the editor of Applied and Environmental Microbiology, ASM.

           

          報告摘要/Abstract:

          The tubular structure of the fungal body requires surface hydrophobicity modulation because absorptive nutrition is efficient if the body is hydrophilic, while reproduction is usually performed by hydrophobic air‐dispersed spores. Therefore, the development of a fungal colony is accompanied by the secretion of various surface-active small secreted cysteine-rich proteins (saSSCPs) such as hydrophobins (HFBs), cerato-platanins (CPs), or others. Located outside the cell, saSSCPs self‐assemble at hydrophobic/hydrophilic interfaces, thereby changing the surface properties and mediating fungal interactions with the environment. Using the HFB and CP enriched molds Trichoderma (Hypocreales) and the saSSCPs-free yeast Pichia pastoris, we unveiled a multitude of novel and unexpected functions of these proteins in fungal lifecycle. In this talk, I will demonstrate that such saSSCPs as HFBs play a pivotal role in Trichoderma development, colony architecture, reproduction, and fitness.

                                         

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